Tryptophan deficiency

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Studies on the Effect of Tryptophan Deficiency on the Metabolic Products of Tryptophan and Niacin.

In 1906, Hopkins and Willcox reported that tryptophan was essential for animals nutrition. Since then, the effect of tryptophan deficiency upon animal nutrition has been discussed by many authors. Recently the interrelation between trypto phan and niacin metabolism was demonstrated. On the other hand, Kotake and his collaborators studied tryptophan metabolism, being especially interested in kyn...

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Maternal dietary tryptophan deficiency alters cardiorespiratory control in rat pups.

Malnutrition during pregnancy adversely affects postnatal forebrain development; its effect upon brain stem development is less certain. To evaluate the role of tryptophan [critical for serotonin (5-HT) synthesis] on brain stem 5-HT and the development of cardiorespiratory function, we fed dams a diet ∼45% deficient in tryptophan during gestation and early postnatal life and studied cardiorespi...

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Tryptophan deficiency and requirements in the adult rat.

T. K. E m '95' Sherman, H. C. & Pappenheimer, A. M. (1920-1). Proc. SOC. exp. Biol., N.Y., 18, 193. Shimotori, N. & Morgan, A. F. (1943). J. bid. Chem. 147, 201. Swift, R. W., Thacker, E. J., Black, A., Uratzler, J. W. &James, W. H. (1947). J. Anim. Sci. 6 , 432. Theiler, A., Green, H. H. & Du Toit, P. J. (1924). J. Dep. Agru. S. Afr. 8, 460. Watson, H. H. (1933). Aust. J . exp. Bwl. med. Sci. ...

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Hydroxykynureninuria: a Case of Abnormal Tryptophan Metabolism Probably Due to a Deficiency of Kynureninase.

During the past decade the route by which tryptophan is converted to nicotinamide has been well studied, but the later stages of the conversion have yet to be fully explained. This tryptophannicotinamide transformation has been shown to occur in mammals (Rosen, Huff and Perlzweig, 1946) and later the formation of labelled nicotinic acid from C14-labelled tryptophan was demonstrated by Heidelber...

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The Effects of Tryptophan Deficiency upon Enzyme Activity in the Rat*

Recently it has been observed that liver enzyme activity may be markedly affected by dietary conditions. Seifter et al. (1) have demonstrated that during complete dietary protein deprivation loss of arginase and n-amino acid oxidase from rat liver occurs more rapidly than loss of general liver protein. We (2) have observed that the level of xanthine oxidase activity in rat liver may be altered ...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1934

ISSN: 0306-3283

DOI: 10.1042/bj0281721